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β-D-(Galβ1-4Glc)-O-(CH2)2-SH
O-glycosylation (α-GalNAc) at Thr131
Fmoc-L-Ser(Galβ(1-3)GalNAc)-OH (Peracetate)
aa length 12) with TF antigen (Galβ1-3GalNAc) at Thr41 and Thr51
96 / Synthetic glycopeptide fragment (Thr1179-Asp1194
PE131020: β-GalNAc-PEG3-DBCO Pack Size:2.5 mg β-D-(Galβ1-4Glc)-O-(CH2)2-SHC33H41N3O10 639. 69 A D N acetylgalactosamine (GalNAc) ligand equipped with a dibenzocyclooctyne (DBCO) handle through a hydrophilic PEG3 spacer. The DBCO group reacts with azides via copper free strain promoted azide alkyne cycloaddition (SPAAC), forming stable 1,2,3 triazole linkages without a copper catalyst. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor
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