Sire of Insanity [Secret Lair Drop Series] 46 {T}: Prevent all combat damage

{T}: Prevent all combat damage that would be dealt by target creature this turn

and you have protection from everything

Set: EX: Sandstorm Type: Colorless Rarity: Uncommon Retreat cost: Colorless

Set: Legends Type: Artifact Rarity: Rare Cost: {6} Creature spells you cast cost up to {2} less to cast

Set: Battle for Zendikar Prerelease Promos Type: Legendary Creature — Eldrazi Rarity: Mythic Cost: {10} When you cast this spell

Sire of Insanity [Secret Lair Drop Series] 46 {T}: Prevent all combat damageSet: Secret Lair Drop Series Type: Creature Demon Rarity: Rare Cost: {4}{B}{R} At the beginning of each end step, each player discards their hand.