AG142015: β-D-GalNAc-Butyl-Carboxylic Acid (Peracetate) Pack Size:250 mg enabling enzymatic chain extension

enabling enzymatic chain extension

used to synthesize peptides modeling early non-enzymatic glycation and advanced glycation end-product (AGE) chemistry

C56H69N3O28 / 1232

protected form of the carboxylic acid that can be hydrolyzed under mild basic conditions (e

Val542 has been labelled with d8

AG142015: β-D-GalNAc-Butyl-Carboxylic Acid (Peracetate) Pack Size:250 mg enabling enzymatic chain extensionC19H29NO11 447. 43 A peracetylated D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a short butyl spacer, with the sugar hydroxyl groups protected as acetate esters. The peracetate groups increase lipophilicity to facilitate cell membrane permeability. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on