So read the table, get a sense of how people are utilizing their interaction, and pick your moment
Murmuration pulls double duty, giving your Birds +1/+1 and vigilance, which is great since it pumps out 1/2 Storm Crow Bird tokens for each spell you've cast on your turn, which can quickly lead to your own army
Knowing How to Build a Commander Deck Will Require All Kinds of Removal Something I see a lot when browsing Magic/Commander topics is folks talking about the lack of removal, or interaction from their opponents
However you build around Karlach, this is a fierce extra combats commander that puts your opponents on notice
However, mana for an activated ability is pretty steep, so running cards that reduce this cost like Zirda, the Dawnwaker and Heartstone are beneficial